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嗎啡違禁品快速檢測(cè)試劑盒
廣州健侖生物科技有限公司
(廣州健侖生物科技有限公司是集研制開發(fā)、銷售、服務(wù)于一體的優(yōu)良企業(yè),公司產(chǎn)品涉及臨床快速診斷試劑、食品安全檢測(cè)試劑,違禁品快速檢測(cè),動(dòng)物疾病防疫檢測(cè)試劑,免疫診斷試劑、臨床血液學(xué)和體液學(xué)檢驗(yàn)試劑、微生物檢驗(yàn)試劑、分子生物學(xué)檢驗(yàn)試劑、臨床生化試劑、有機(jī)試劑等眾多領(lǐng)域,同時(shí)核心代理Panbio、FOCUS、Qiagen、IBL、CORTEZ、Fuller、Inbios、BinaxNOW、LumuQuick、日本富士、日本生研等多家有名診斷產(chǎn)品集團(tuán)公司產(chǎn)品,致力于為商檢單位、疾病預(yù)防控制中心、海關(guān)出入境檢疫局、衛(wèi)生防疫單位,緝毒系統(tǒng),戒毒中心,檢驗(yàn)檢疫單位、生化企業(yè)、科研院所、醫(yī)療機(jī)構(gòu)等機(jī)構(gòu)與行業(yè)提供*、高品質(zhì)的產(chǎn)品服務(wù)。此外,本公司還開展食品、衛(wèi)生、環(huán)境、藥品等多方面的第三方檢測(cè)服務(wù)。)
嗎啡違禁品快速檢測(cè)試劑盒
嗎啡(Morphine,MOP)是片類一種,在片中的含量為4%-21%,平均10%左右?;瘜W(xué)名稱17-甲基-4,5α-環(huán)氧-7,8-二脫氫嗎啡喃-3,6α-二醇。化學(xué)式為C17H19NO3,分子量為285.34,以口服形式為主。
對(duì)嗎啡的檢測(cè)常用的方法有化學(xué)顯色法、薄層層析檢測(cè)法(TLC)、高效液相色譜檢測(cè)法(HPLC)和氣質(zhì)聯(lián)
用色譜檢測(cè)法(GC/MS)法等。前兩者需要大量檢測(cè)樣品,靈敏度及精密度均不高;后兩者雖有較高的靈敏度及精密度,但檢測(cè)要求高,也難以推廣。免疫檢測(cè)法可能是未來的發(fā)展方向之一。[4-5]
化學(xué)顯色法
(1)取本品約1mg,加甲醛硫酸試液1滴,即顯紫堇色。
(2)取本品約1mg,加鉬硫酸試液0.5ml,即顯紫色,繼變?yōu)樗{(lán)色,zui后變?yōu)樽鼐G色。
(3))取本品約1mg,加水1ml溶解后,加稀鐵試液1滴,即顯藍(lán)綠色(與可待因的區(qū)別)。
含量
取本品約0.2g,精密稱定,加冰醋酸10ml與試液4ml溶解后,加結(jié)晶紫指示液1滴,用高氯酸滴定液(0.1mol/L )滴定至溶液顯綠色,并將滴定的結(jié)果用空白試驗(yàn)校正。每1ml高氯酸滴定液(0.1mol/L )相當(dāng)于32.18mg的C17H19NO3?HCl。
巨噬細(xì)胞表面有多種受體,有的能 與抗體結(jié)合(Fc受體);有的能與
補(bǔ)體結(jié)合(C3受體);有的能與纖維 粘連蛋白結(jié)合(纖維粘連蛋白受
體),在特異性吞噬過程中,抗體, 補(bǔ)體、纖維粘連蛋白作為識(shí)別細(xì)
菌子先將細(xì)菌、病毒、異體細(xì)胞、受 損傷的細(xì)胞等包裹起來,通過它
們與巨噬細(xì)胞表面相應(yīng)的受體結(jié)合, 才能被巨噬細(xì)胞識(shí)別和粘附,啟
動(dòng)巨噬細(xì)胞的吞噬過程,并顯著增強(qiáng) 吞噬作用(圖3-7)。這種免疫
吞噬作用是巨噬細(xì)胞重要的功能特征 。
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【公司名稱】 廣州健侖生物科技有限公司
【市場(chǎng)部】 楊永漢
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【騰訊 】 2042552662
【公司地址】 廣州清華科技園創(chuàng)新基地番禺石樓鎮(zhèn)創(chuàng)啟路63號(hào)二期2幢101-103室
Morphine (Morphine, MOP) is a tablet drug, the content in the film is 4% -21%, an average of about 10%. Chemical Name 17-Methyl-4,5α-epoxy-7,8-didehydromorphinan-3,6α-diol. Chemical formula C17H19NO3, molecular weight of 285.34, mainly oral form.
Common methods for the detection of morphine are chemical chromotography, TLC, HPLC and GC / MS
Chromatography (GC / MS) method. The first two require a large number of test samples, sensitivity and precision are not high; the latter two despite the higher sensitivity and precision, but the detection of high demand, it is difficult to promote. Immunodetection may be one of the future directions of development. [4-5]
Chemical colorimetry
(1) Take about 1mg of this product, add 1 drop of formaldehyde sulfuric acid test solution, that is significant purple pansy color.
(2) Take about 1mg of this product, add 0.5ml of molybdate sulfuric acid test solution, which is purple, then change to blue, and finally turn brown.
(3)) Take about 1mg of this product, add 1ml of water and dissolve. Add 1 drop of dilute potassium ferricyanide test solution, that is blue-green (difference from codeine).
content
Take this product about 0.2g, accuray weighed, add glacial acetic acid 10ml and 4ml mercury acetate solution dissolved, add crystal violet indicator solution 1 drop, perchloric acid titration solution (0.1mol / L) titration until the solution was green, Titration and the results of a blank test correction. Per 1ml perchloric acid titrant (0.1mol / L) is equivalent to 32.18mg of C17H19NO3?HCl.
Macrophages have a variety of receptors on the surface, and some can bind to antibodies (Fc receptors); some can interact with
Complement fixation (C3 receptor); some can bind to fibronectin (fibronectin
Body), in the process of specific phagocytosis, antibodies, complement, fibronectin as a recognition fine
Mycoplasma first bacteria, viruses, allogeneic cells, damaged cells, etc. wrapped up through it
They and macrophage receptors on the surface of the corresponding combination of macrophages can be recognized and adhesion, Kai
Phagocytosis of macrophages and significantly enhance phagocytosis (Figure 3-7). This immunity
Phagocytosis is an important functional feature of macrophages.